The ENBDC started in 2006 as a means of bringing together worldwide laboratories working on breast development and cancer. The idea was to raise awareness of each other’s research in order to foster contact, encourage technical exchange and collaboration, especially across disciplines, as well as to offer intellectual and information resources to the breast cancer research community as a whole. The ENBDC was formally instigated in 2007, initially as a web-based contact list of interested laboratories, and in May 2008 the ENBDC website ‘went live’. Twelve Annual Methods Workshops (2009-2022), kindly supported by various sponsors have been held in Weggis, Switzerland. The meetings are a resounding success, promoting discussion and interaction as well as inter-laboratory visits by researchers keen to see the specifics of individual methods at first hand. Reports of these meetings were published in Breast Cancer Research and Journal of Mammary Gland Biology and Neoplasia.