Lalage Wakefield

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National Cancer Institute
TGF-beta pathway in mammary gland development and neoplasia. Development of TGF-beta path targeted therapeutics. Metastasis. Breast cancer stem cells.
Transcriptomics, Chip-Chip/Seq, RNAi, confocal microscopy, transgenesis, ex vivo metastasis assays, immunophenotyping, techniques for quantitative analysis of TGF-beta pathway
Human xenograft, mouse syngeneic transplant, genetically engineered mouse breast cancer models