Mario P. Tschan

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Experimental Pathology, TP2, University of Bern
Autophagy (Autophagic Pathways in Myeloid Development and Resistance Mechanisms), Resistance Mechanisms in Targeted Cancer Therapies (Breast and Lung Cancer, Acute Myeloid Leukemias), Retinoid Acid Therapy, Apoptosis, Transcription Factors and microRNAs Regulating ATG Genes and Genes involved in AML Differentiation/Cell Survival
Lentiviral vectors (KD, overexpression, constitutive/inducible), Autophagy detection (GFP-RFP-LC3B tandem constructs, long-lived protein degradation analysis, endogenous LC3B detection in Cells and FFPE tissue,...), AML and Breast Cancer Cell Line Models, Tissue Micro Arrays, Proximity Ligation Assays, Promoter Reporter and ChIP assays, FACS, RNA and Protein Analyses
Human Breast Cancer Cell Line Models, Breast Cancer Patient Samples (TMA), Mammospheres, Establishing 3D Perfusion Reactor for Breast Cancer (Cell Lines and Primary Tissue)