Experimental Oncology European Institute of Oncology and the Campus IFOM-IEO
1.Hematopoietic stem cells and Acute Myeloid Leukemias 2. Breast stem cells and breast cancer 3.Effects of checkpoint activation on tissue homeostasis and molecular mechanisms of aging 4. Epigenetics and environmental cancer risk assessment
Cell culture (primary cell culture; cell lines) and mouse models; 3D cultures; xenografts; standard molecular and cell biology techniques; time-lapse microscopy; FACS sorting; siRNA technology; DNA microarrays, tissue microarrays; ChIP, ChIP-chip and ChIP-Seq.
Mammospheres; KO and transgenic mice, humanized mouse, conditional and constitutive models