Stewart Martin

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+44 (0)1158231846
University of Nottingham, School of Medicine, Division of Cancer and Stem Cells, Department of Clinical Oncology, Nottingham City Hospital, Nottingham NG5 1PB
Prognostic and predictive biomarkers; Proteases (Calpains and Calpastatin); REDOX metabolism (biomarkers and novel inhibitors); Lymphatic cell biology (lymphovasular invasion);Radiation Biology (predictive biomarkers of radiotheraputic response, drug/radiation interactions).
In vitro: invasion (incl endothelial transmigration), adhesion and migration (haptotaxis); usual molecular techniques (Westerns, Q-RT-PCR, si- & shRNA etc); Immunohistochemistry; Cell X-ray irradiation facility (+/- hypoxia)
In vitro models (2D and 3D (matrigel)) with normal and malignant cells +/- stromal interactions; vascular and lymphatic endothelium (primary and established lines); tissue microarrays (histopathology based studies).